Design, construction and testing of novel instruments, which provide sample environment at the extremes of pressures, temperatures, electric and magnetic fields.  Deveolopment of high-pressure equipment used for diffraction, spectroscopy, magnetic and eletric transport measurements in-house and at large scale neutron and synchrotron facilities.  Computer moedeling of stresses and deformations as well as temperature and field gradients in materials and equipment performing in extreme conditions.  Studies of magnetic, electronic and structural properties of materials at high pressure.